Why Psychedelic Delivery Mechanisms Matter
October 2nd, 2020
App, Exclusive, News, Psychedelics, Top News
The psychedelics industry is poised to become a nearly $7 billion market by 2027, according to Data Bridge Market Research, driven by the potential to revolutionize the treatment of mental health disorders. While investors have many options in the space, the best positioned companies are combining delivery mechanisms with novel compounds to create IP strategies.
Let’s take a look at why delivery mechanisms matter and how Cybin Corp. is leveraging sublingual delivery to revolutionize psychedelic therapies.
What Are Delivery Mechanisms?
Most pharmaceuticals come from natural sources—and the same is true for both cannabis and psychedelics. Of course, the final product that people pick up from the pharmacy is typically pill, capsule, spray, suppository or other delivery mechanism.
Delivery mechanisms play an important role in ensuring the bioavailability and optimal delivery of pharmaceutical compounds. For instance, extended release tablets slowly release an active pharmaceutical ingredient, or API, over time rather than all at once. These capabilities can be transformative for chronic pain relief therapies by making a once-a-day option.
Aside from convenience and performance, delivery mechanisms may be required for any efficacy. The most common problem experienced by some pharmaceuticals is first-pass metabolism in the liver. While it’s possible to simply increase the dosage, there are many instances where high doses become toxic, making a delivery mechanism essential.
Benefits of Delivery Mechanisms
The most obvious benefit of a delivery mechanism is that it improves the performance of a pharmaceutical compound or makes it safe to use. But aside from these benefits, there are several other reasons to develop innovative delivery mechanisms.
Delivery mechanisms are a common way to patent natural compounds or extend expiring patents. While patients and consumers can still access cheap natural compounds or legacy products, these delivery mechanisms typically improve the efficacy of the compound or offer other benefits that may encourage commercial adoption.
The development of delivery mechanisms themselves also represents unique intellectual property. Investors in these companies benefit from both a potentially efficacious and unique delivery, as well as the ability to leverage the same delivery technology across a wide range of different compounds—or even the ability to license it to others.
Cybin’s Psychedelic Approach
Cybin Corp. is focused on psychedelic drug development, unique delivery mechanisms, improved novel compounds and protocols that target psychiatric and neurological conditions.
Watch Cybin CEO Doug Drysdale discuss the innovative delivery mechanism:
The company’s wholly owned subsidiary, Serenity Life Sciences, has developed a fast-acting sublingual delivery strip technology that provides both improved bioavailability and greater convenience for patients. In particular, sublingual delivery offers fast access to the bloodstream and bypasses second-pass metabolism in the liver.
The unique delivery mechanism is being used in a Phase II randomized, parallel group, bioequivalence study of psilocybin for the treatment of Major Depressive Disorder. If successful, the company could become one of the first life science companies to launch a fully approved psilocybin product targeting depression.
Watch CEO Doug Drysdale outline the company’s clinical trial strategy:
Cybin Corp. could become one of the first life sciences companies to commercialize psilocybin for the treatment of depression. With an innovative delivery mechanism, the company developed a patentable product with potentially significant advantages over other forms of psilocybin, creating an attractive commercial opportunity.
The company plans to go public through a reverse-takeover of Clarmin Explorations on the TSX Venture exchange. In connection with the going public transaction, the company plans to raise a minimum of $14 million and a maximum of $21 million to fund its ongoing research and development activities.
For more information, visit the company’s website or download the investor presentation.
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