InMed Pharma Advances Clinical Trials with CRO Deal
June 14th, 2017
News, Top News
The widespread potential for cannabinoids is quickly being recognized by the pharmaceutical industry as companies rush to develop therapeutics targeting many medical conditions. While GW Pharmaceuticals plc (NASDAQ: GWPH) is the most well-known company in the space, investors should consider many other companies that are rapidly advancing therapeutics that could become the next blockbuster drugs.
In this article, we will look at InMed Pharmaceuticals Inc. (CSE: IN) (OTCQB: IMLFF) and the progress it is making in advancing its lead clinical trial candidate.
Innovative Clinical Program
InMed Pharma is a pre-clinical stage biopharmaceutical company that specializes in the development of cannabinoid-based prescription drug therapies that leverage its novel drug delivery systems. Using a proprietary bioinformatics database, the company rapidly identifies cannabinoid compounds with the potential to address serious medical conditions. This process enables the company to efficiently develop highly-specialized therapies across many conditions.
The company’s proprietary Bioinformatics platform uses algorithms to assess the different active sites on cannabinoids and screen them against approved drug structures, disease site receptors, genetic profiles of diseases, and the involvement of proteins and chemical metabolites in disease pathways. The goal is to select specific cannabinoids – or combinations of cannabinoids – that may play a role in regulating diseases, with a higher likelihood of success.
InMed’s Biosynthesis process then takes over, differing from many large competitors such as GW Pharmaceuticals, in that the company can access minor cannabinoids that are currently economically unfeasible to develop into drugs. InMed quickly and economically replicates niche cannabinoids by injecting their DNA into an E. coli cell that rapidly divides – a process similar to the way insulin is produced on a massive scale to help millions of diabetics around the world.
Beginning Pre-Clinical Trials
InMed Pharma’s lead clinical program is INM-750 targeting epidermolysis bullosa (EB), which is a condition affecting about 50,000 patients across North America, Europe, and Japan. While the condition has no approved treatments, Scioderm was recently acquired by Amicus in September 2015 for $847 million with its Phase III Zorblisa™ program. JP Morgan and Cowen research reports estimated peak sales of $900 million to $1.2 billion for the drug. Zorblisa™ is being evaluated as a therapy for the treatment of lesions and blistering, two symptoms associated with EB.
The company’s INM-750 has several mechanisms of action in the skin to deliver symptomatic relief, including accelerated wound healing, pain reduction, itch reduction, reduced inflammation, and antimicrobial activity. In addition, the therapeutic may re-establish the epidermal-dermal junction by upregulating specific keratins in the skin, which could essentially reverse the disease.
On June 13th, the company announced an agreement with Pharmaseed Ltd., Israel’s largest GLP-certified pre-clinical contract research organization, to develop a final formulation of INM-750 for continued R&D, including IND-enabling pharmacology and toxicology studies and subsequent clinical studies. The move marks the first step on the pathway to approval status, which management anticipates sometime in the next 4-5 years.
Completing this important phase is a major step forward in InMed’s development program. Not only will it enable the EB study, but completing the toxicology and formulation processes could make those steps much more efficient for future potential trials in other wound healing applications.
InMed Pharmaceuticals Inc. (CSE: IN) (OTCQB: IMLFF) represents a compelling investment opportunity in the cannabinoid therapeutics space. In addition to INM-750, the company has two other R&D programs targeting glaucoma and pain management. The early clinical results from these programs could generate significant catalysts for investors over the coming years and help propel shares significantly higher over the long-term.
With a market capitalization of just about $20 million, the company trades at a fraction of its potential if successful in commercializing its clinical pipeline. Management’s engagement of a reputably CRO represents an important next step in preparing for the clinical trial process that could generate significant catalysts for the company.
Follow Us on Social Media
About CFN Media
CFN Media (CannabisFN) is the leading creative agency and media network dedicated to legal cannabis. We help marijuana businesses attract investors, customers (B2B, B2C), capital, and media visibility. Private and public marijuana companies and brands in the US and Canada rely on CFN Media to grow and succeed.
CFN launched in June of 2013 to initially serve the growing universe of publicly traded marijuana companies across North America. Today, CFN Media is also the digital media choice for the emerging brands in the space.
Disclaimer: Matters discussed on this website contain forward-looking statements that are subject to certain risks and uncertainties that could cause actual results to differ materially from any future results, performance or achievements expressed or implied by such statements. Emerging Growth LLC dba TDM Financial, which owns CannabisFN, is not registered with any financial or securities regulatory authority and does not provide nor claims to provide investment advice or recommendations to readers of this release. Emerging Growth LLC dba TDM Financial, which owns CannabisFN, may from time-to-time have a position in the securities mentioned herein and will increase or decrease such positions without notice. The Information contains forward-looking statements, i.e. statements or discussions that constitute predictions, expectations, beliefs, plans, estimates, or projections as indicated by such words as "expects", "will", "anticipates", and "estimates"; therefore, you should proceed with extreme caution in relying upon such statements and conduct a full investigation of the Information and the Profiled Issuer as well as any such forward-looking statements. Any forward looking statements we make in the Information are limited to the time period in which they are made, and we do not undertake to update forward looking statements that may change at any time; The Information is presented only as a brief "snapshot" of the Profiled Issuer and should only be used, at most, and if at all, as a starting point for you to conduct a thorough investigation of the Profiled Issuer and its securities and to consult your financial, legal or other adviser(s) and avail yourself of the filings and information that may be accessed at www.sec.gov, www.pinksheets.com, www.otcmarkets.com or other electronic sources, including: (a) reviewing SEC periodic reports (Forms 10-Q and 10-K), reports of material events (Form 8-K), insider reports (Forms 3, 4, 5 and Schedule 13D); (b) reviewing Information and Disclosure Statements and unaudited financial reports filed with the Pink Sheets or www.otcmarkets.com; (c) obtaining and reviewing publicly available information contained in commonlyknown search engines such as Google; and (d) consulting investment guides at www.sec.gov and www.finra.com. You should always be cognizant that the Profiled Issuers may not be current in their reporting obligations with the SEC and OTCMarkets and/or have negative signs at www.otcmarkets.com (See section below titled "Risks Related to the Profiled Issuers, which provides additional information pertaining thereto). For making specific investment decisions, readers should seek their own advice and that of their own professional advisers. Emerging Growth LLC dba TDM Financial, which owns CannabisFN, may be compensated for its Services in the form of cash-based and/or equity-based compensation in the companies it writes about, or a combination of the two. For full disclosure, please visit: http://www.cannabisfn.com/legal-disclaimer/. A short time after we acquire the securities of the foregoing company, we may publish the (favorable) information about the issuer referenced above advising others, including you, to purchase; and while doing so, we may sell the securities we acquired. In addition, a third-party shareholder compensating us may sell his or her shares of the issuer while we are publishing favorable information about the issuer. Except for the historical information presented herein, matters discussed in this article contain forward-looking statements that are subject to certain risks and uncertainties that could cause actual results to differ materially from any future results, performance or achievements expressed or implied by such statements. Emerging Growth LLC dba TDM Financial, which owns CannabisFN, is not registered with any financial or securities regulatory authority, and does not provide nor claims to provide investment advice or recommendations to readers of this release. Emerging Growth LLC dba TDM Financial, which owns CannabisFN, may from time to time have a position in the securities mentioned herein and will increase or decrease such positions without notice. For making specific investment decisions, readers should seek their own advice and that of their own professional advisers. Emerging Growth LLC dba TDM Financial, which owns CannabisFN, may be compensated for its Services in the form of cash-based and/or equity- based compensation in the companies it writes about, or a combination of the two. For full disclosure please visit: http://www.cannabisfn.com/legal-disclaimer/.