CURE Pharma Looks to Revolutionize Cannabinoid Delivery
June 15th, 2017
News, Top News
Many successful pharmaceutical products rely on both efficacious chemical compounds and an effective delivery system. While many companies outsource one or the other, there are some companies that have developed both pieces of the puzzle, which enables them to rapidly bring successful products to market without diluting ownership. These companies also have the ability to generate licensing revenue through deals with third parties.
In this article, we will look at CURE Pharmaceutical Inc.’s (OTCQB: CURR) Oral Thin Film technology and why it could be a game-changer in the cannabis industry.
Oral Thin Film Technology
CURE Pharma’s CureFilm™ is a patented multi-layer oral thin film designed to improve the pharmacokinetic profile and overall therapeutic index of active pharmaceutical ingredients (APIs). The product can be administered without water to the tongue, cheek, or sublingual regions of the mouth and enables medications to enter the bloodstream enterically, buccally, or sublingually for maximum dosage while providing better flavor masking than other formulations.
The technology has many advantages over other delivery systems (see Figure 1). CureFilm™ is more stable, durable, and faster acting than other oral delivery mechanisms. Greater palatability improves medication adherence and increased bioavailability helps maximize the effectiveness of APIs.The product requires no water to administer making it easier to take, particularly for children, elderly patients, animals, and others that may have trouble swallowing pills. In fact, the Harris Institute did a study that shows that 40% of adults have trouble swallowing pills, creating a huge market for a substitute to traditional pills.
Figure 1 – CureFilm™ Benefits – Source: CURE Pharma Website
The delivery technology can be applied to many different pharmaceuticals, which makes it a compelling “platform play” for investors. For instance, pharmaceutical companies facing near-term patent expirations may leverage the new delivery technology as a way to extend patent life by reformulating products. The drug companies benefit from the extended patent life while the company benefits from potential licensing or royalty payments.
Applications in Cannabis
The cannabis industry is increasingly moving toward non-smoked delivery mechanisms for tetrahydrocannabinol (THC), cannabidiol (CBD), and other cannabinoids. In fact, edibles are the fastest growing segment of the emerging cannabis industry, representing over 40% of the market by some accounts. Many pharmaceutical companies have also embraced capsules and pills as a more palatable way to deliver medication for physicians and their patients.
CURE Pharma recently announced the first-ever ex-vivo clinical study of cannabinoid compounds to treat leukemia and prostate cancer in partnership with the Technion Israel Institute of Technology. There is strong anecdotal evidence that cannabinoids can help in these cases, but the company’s goal is to put some science into the theories. CURE will identify the appropriate cannabinoid molecules to study and Technion will conduct the study.
The company anticipates having some early data within the first six months following an in-vitro study. Since the studies are being conducted in Israel, the company anticipates getting to human clinical trials in a much shorter timeframe than possible in the United States. The strategy is to develop new chemical entities from the research that can be patented before undergoing robust clinical trials in the United States under the eyes of the FDA.
CURE Pharmaceutical (OTCQB: CURR) represents a compelling investment opportunity within the cannabis industry given its unique delivery mechanism and cancer-focused research and development. With the ability to license-out its CureFilm™, the company could generate significant near-term revenue as it develops cannabinoid-based cancer therapeutics in Israel that can then be patented and developed in the United States.
For more information, visit the company’s website.
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